HMGB1 and anti-HMGB1 antibodies in HIV-infected patients with neurological disorders especially

摘要

An in vitro method of quantifying specific antibodies for Case High Mobility Group I (HMGB1) contained in a cerebrospinal fluid sample obtained from a subject, comprising: a) contacting said cerebrospinal fluid sample with native HMGB1 protein HMGB1 protein or derivatives as long as these derivatives bind to antibodies specific for HMGB1; b) quantifying the antibodies specific for HMGB1. .