Non-invasive in-vivo measurement apparatus and measurement method by Raman spectroscopy

摘要

A metabolite concentration is measured in vivo using Raman spectroscopy in such a way as to receive at a detector (229) light scattered from the metabolite in interstitial fluid in skin in a measurement location (217) at a depth (218) of from 200-300 m below the skin surface providing improved retention of correct calibration and transferability of calibration between individual subjects.