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Methods for Novel Drug Discovery, Treatment And Selective Targeting for Gefitinib-Resistant Non-Small-Cell Lung Cancer Harboring T790M Mutation

机译:T790M突变的吉非替尼耐药的非小细胞肺癌的新型药物发现,治疗和选择性靶向的方法。

摘要

The present invention relates to methods for novel drug discovery, treatment and selective targeting for Gefitinib-resistant non-small-cell lung cancer (NSCLC) harboring an additional mutation, in particular, to the discovery of a drug candidate or agent identified by the presently claimed method for use in treating and selective targeting Gefitinib-resistant NSCLC harboring T790M mutation.
机译:本发明涉及具有额外突变的针对吉非替尼耐药的非小细胞肺癌(NSCLC)的新药发现,治疗和选择性靶向的方法,尤其涉及发现目前鉴定的候选药物或药物的方法要求保护的方法用于治疗和选择性靶向具有T790M突变的耐吉非替尼的NSCLC。

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