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Method and an insertable medical device for delivering one or more pro-healing agents to a target site within a blood vessel post-deployment of a stent
Method and an insertable medical device for delivering one or more pro-healing agents to a target site within a blood vessel post-deployment of a stent
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机译:用于在支架的部署后将一种或多种促愈剂递送至血管内的目标部位的方法和可插入医疗装置
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摘要
The invention discloses an insertable medical device for delivering one or more pro-healing agents to a site of deployment of a stent in a blood vessel. The surface of the insertable medical device is coated with nano-carriers that include the one or more pro-healing agents encapsulated with one or more biological agents. The nano-carriers are released when the insertable medical device is expanded at the site. The nano-carriers thus released penetrate tissues at the site resulting in dissolution of the one or more biological agents. Thereafter, the one or more pro-healing agents are released from the nano-carriers at the site. Thus, an in-tissue release of the one or more pro-healing agents at the site is achieved thereby improving endothealization, extracellular matrix formation and healing at the site post deployment of the stent in the blood vessel.
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