首页> 外国专利> Method for diagnosing of thyroid papillous carcinoma, application of microRNA marker for diagnosing of the thyroid carcinoma, assessment of the disease progress and evaluation of patient and/or disease susceptibility to the proposed treatment and diagnostic set containing such markers

Method for diagnosing of thyroid papillous carcinoma, application of microRNA marker for diagnosing of the thyroid carcinoma, assessment of the disease progress and evaluation of patient and/or disease susceptibility to the proposed treatment and diagnostic set containing such markers

机译:甲状腺乳头状癌的诊断方法,microRNA标记物在甲状腺癌的诊断中的应用,疾病进展的评估以及对含有这种标记物的拟议治疗和诊断工具的患者和/或疾病易感性的评估

摘要

the subject of the invention is a way of diagnosing the lesion such as tumor and / or change in mild thyroid in a patient who's way includes: - providing patient samples originating from biological, determination of the quantity of one or more selected from the group including mikrorna development mir 146b - 5p, mir 146b - 3p, mir - 221 - 5p, mir - 221 - mir - 222 - 3p, 5p, mir - 222 - 3p,mir - 181 - 5p and mir - 182 - 5p in biological sample, - comparing expression mikrorna level mikrorna expression in the control group, the diagnosis of cancer and / or changes of mild patients, if the level of expression in the biological sample mikrorna is amended terms of level expression observed in samples of biological fluids in the control group.the subject of the invention is also applicable mikrorna marker to diagnose the lesion in the thyroid and kit for diagnosis of the lesion.
机译:本发明的主题是一种在患者中诊断诸如肿瘤和/或轻度甲状腺变化的病变的方法,该方法包括:-提供源自生物学的患者样品,确定选自该组的一种或多种的量包括mikrorna development生物学中的mir 146b-5p,mir 146b-3p,mir-221-5p,mir-221-mir-222-3p,5p,mir-222-3p,mir-181-5p和mir-182-5p -如果比较生物样品中mikrorna的表达水平,则比较对照组中mikrorna的表达水平,诊断癌症和/或轻度患者的变化,以比较mikrorna的表达水平。本发明的主题还适用于mikrorna标记物以诊断甲状腺中的病变和用于诊断病变的试剂盒。

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