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Methods for determining the propensity of a patient for hemorrhagic transformation after stroke
Methods for determining the propensity of a patient for hemorrhagic transformation after stroke
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机译:确定患者中风后出血转化倾向的方法
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摘要
The invention relates to a method for predicting the risk of suffering symptomatic hemorrhagic transformation in response to the treatment with a thrombolytic agent in an ischemic stroke patient based on the determination of the level of Nurr1 in a sample of said patient. Furthermore the invention relates to a composition comprising a Nurr1 inhibitor and a thrombolytic agent and to a pharmaceutical preparation comprising the composition of the invention and a pharmaceutically acceptable excipient or carrier. The invention also relates to the use of an inhibitor of Nurr1 in the treatment of cytotoxicity associated to the treatment with a thrombolytic agent and to the use of the composition and the pharmaceutical preparation of the invention in the treatment of ischemic stroke.
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