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METHOD FOR PRODUCING RADIOZOTOPA LU-177

机译:method for producing radio Z o top ALU-177

摘要

1. A method for producing a radioisotope 177Lu, comprising irradiation with neutrons in a nuclear reactor of the target isotope 176Yb, operating time of the reaction 176Yb (n, γ) 177Yb □ 177Lu target radioisotope 177Lu, dissolving the irradiated target direction solution with 177Lu and 176Yb on an ion exchange column, deposition column 176Yb and 177Lu solution and subsequent separation and 177Lu 176Yb, characterized in that the 177Lu and 176Yb separated by chromatography by first eluting from the ion exchange chromatography column 177Lu, leaving ytterbium onto a column direction on the second eluate th ion exchange chromatographic column, 177Lu sorption in the second column, the eluate directions to waste, followed by elution with a second 177Lu.2 column. A method according to claim 1, characterized in that the target isotope 176Yb use ytterbium oxide (176Yb2O3) .3. A method according to claim 1, characterized in that as eluant eluted 177Lu a first ion exchange column using 0.07 N solution of α - isobutyric kisloty.4. A method according to claim 1, characterized in that as eluant eluted 177Lu with a second ion exchange column using 0.5 N HCl.5. A method according to claim 1, characterized in that the ion exchange resin in the first column use cationite KU-2-8 a + NH4 - forme.6. A method according to claim 1, characterized in that the ion exchange resin in the second column is used cationite KU-2-8 a + H - form.
机译:1.一种生产放射性同位素177Lu的方法,包括在靶同位素176Yb的核反应堆中用中子辐照,反应176Yb(n,γ)177Yb□177Lu的目标放射性同位素177Lu的操作时间,用177Lu溶解被辐照的目标方向溶液然后,在离子交换柱,沉积柱176Yb和177Lu溶液以及随后的分离和177Lu 176Yb上分离出176Yb和176Yb,其特征在于,首先通过色谱法从离子交换色谱柱177Lu上洗脱,通过色谱法分离177Lu和176Yb,使leaving向柱上的方向第二个洗脱液为离子交换色谱柱,在第二个柱上进行177Lu吸附,洗脱方向为废液,然后用第二个177Lu.2柱洗脱。 2.根据权利要求1所述的方法,其特征在于,所述目标同位素176Yb使用氧化oxide(176Yb2O3).3。 2.根据权利要求1所述的方法,其特征在于,使用0.07N的α-异丁酸Kisloty溶液将第一离子交换柱洗脱为177Lu。 2.根据权利要求1所述的方法,其特征在于,作为洗脱剂,使用0.5N HCl.5用第二离子交换柱洗脱177Lu。 2.根据权利要求1所述的方法,其特征在于,所述第一塔中的离子交换树脂使用阳离子沸石KU-2-8a + NH 4-甲酸酯。 2.根据权利要求1所述的方法,其特征在于,第二塔中的离子交换树脂以阳离子阳离子KU-2-8a + H-形式使用。

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