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AGGREGATED CELL EVALUATION METHOD AND AGGREGATED CELL EVALUATION DEVICE

机译:融合细胞评价方法及融合细胞评价装置

摘要

An aggregated cell evaluation apparatus 1 includes a laser light source 10, a speckle image acquisition unit 20, an SC calculation unit 30, an evaluation unit 40, and a memory unit 50. The speckle image acquisition unit 20 acquires a two-dimensional speckle image by forward scattered light generated in aggregated cells 90 by irradiation of the aggregated cells 90 with laser light output from the laser light source 10. The SC calculation unit 30 calculates a speckle contrast value K n of a speckle image In at each time t n , determines a maximum value K max among the speckle contrast values K 1 to K N , and normalizes the speckle contrast value K n at each time t n by the maximum value K max to obtain a normalized speckle contrast value K n '. The evaluation unit 40 evaluates motion of the aggregated cells 90, based on the normalized speckle contrast value K n ' at each time t n . This realizes a method and an apparatus capable of readily evaluating the motion of aggregated cells.
机译:聚集细胞评估设备1包括激光源10,斑点图像获取单元20,SC计算单元30,评估单元40和存储单元50。斑点图像获取单元20获取二维斑点图像。通过利用从激光源10输出的激光照射聚集细胞90而在聚集细胞90中产生的前向散射光。SC计算单元30计算在每个时间tn处的斑点图像In的斑点对比度值K n,在斑点对比值K 1到KN中将最大值K max标准化,并且将在每个时间tn的斑点对比值K n标准化为最大值K max,以获得标准化的斑点对比值K n'。评估单元40基于在每个时间t n处的归一化散斑对比度值K n'来评估聚合单元90的运动。这实现了能够容易地评估聚集的细胞的运动的方法和设备。

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