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Methods and compositions for inhibiting clostridium difficile spore germination and outgrowth

机译：抑制艰难梭菌孢子萌发和长出的方法和组合物

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摘要

Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile-associated diseases, including but not limited to C. difficile colitis.

机译：某些胆汁酸，包括新型胆汁酸及其衍生物可用于抑制I C的萌发。艰难的孢子和/或 C的生长。困难的细胞。本发明的方法和组合物可用于预防和治疗I C。难感性相关疾病，包括但不限于 C。难治性结肠炎。 展开▼

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公开/公告号US9340569B2

专利类型

公开/公告日2016-05-17

原文格式PDF

申请/专利权人 JOSEPH SORG;ABRAHAM L. SONENSHEIN;
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申请/专利号US200913126687

发明设计人 JOSEPH SORG;ABRAHAM L. SONENSHEIN;
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申请日2009-11-02

分类号A61K31/575;C07J9;

国家 US

入库时间 2022-08-21 14:32:11

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