Digit Splint Device For Mallet Finger Injury and Other Method of Use

• 1. 一种用于手指骨折康复的固定夹板 [P] . 中国专利： CN215080498U . 2021-12-10
• 2. 一种用于手指骨折恢复的指骨夹板 [P] . 中国专利： CN208096855U . 2018.11.16
• 3. Digit splint for phalangeal fractures or mallet finger injury [P] . 美国专利： US2005027223A1 . 2005-02-03

  机译： 手指夹板用于指骨骨折或槌状指伤

• 4. An improved digit splint for phalangeal fractures or mallet finger injury [P] . AUPS268702A0 . 2002-06-20

  机译： 一种改进的指骨夹板，用于指骨骨折或槌状指伤

• 5. Mallet finger splint and method for securing such a mallet finger splint. [P] . 瑞士专利： CH709103A1 . 2015-07-15

  机译： 槌状手指夹板和用于固定这种槌状手指夹板的方法。

• 1. Three Reverse Adipofascial Cross Finger Flaps Used for Coverage of Raw Areas on Two Fingers of a Patient with Blast Injury of the Hand—Case Report [J] . Medhat Emil, Anood Alqaydi, Dalal AlMansoori, 现代整形外科（英文） . 2020,第003期
• 2. Methods and Devices of Speckle-Noise Suppression (Review) [J] . Igor Kompanets, Nikolay Zalyapin 光学与光子学期刊（英文） . 2020,第010期
• 3. Numerical methods for the magneto-mechanical coupling analysis of in-vessel components in Tokamak devices [J] . Xudong Li, Shejuan Xie, Cuixiang Pei, 力学快报(英文版) . 2019,第003期
• 4. A prospective randomized controlled trial comparing night splinting with no splinting after treatment of mallet finger [J] . Jillian S. Gruber, Arjan G. J. Bot, David Ring Hand . 2014,第2期
• 5. Single blind, prospective, randomized controlled trial comparing dorsal aluminum and custom thermoplastic splints to stack splint for acute mallet finger. [J] . OBrien LJ, Bailey MJ Archives of Physical Medicine and Rehabilitation . 2011,第2期
• 6. The Kleinert modified dorsal finger splint for mallet finger fracture. [J] . Hart RG, Kleinert HE, Lyons K The American journal of emergency medicine . 2005,第2期
• 7. Finger Blockage Mitigation Method for mmWave Beamforming Mobile Devices [C] . Youngno Youn, Dongkwon Choi, Wonbin Hong IEEE International Symposium on Antennas and Propagation . 2019
• 8. Investigation of Extrinsic Finger and Thumb Muscles to Command Individual Digits on a Multi-Functional Artificial Hand [D] . Birdwell, Jay Alexander 2012
• 9. Patient-specific 3D-printed Splint for Mallet Finger Injury [O] . Ali Zolfagharian, Timothy M. Gregory, Mahdi Bodaghi, 2020
• 10. Is the Use of Biodegradable Devices in the Operative Treatment of Avulsion Fractures of Fingers, the So-Called Mallet Finger Advantageous? A Feasibility Study with Meniscus Arrows® [O] . Nelis, R, Wouters, D.B 2008
• 11. Development of a Dynamic Internal Splint for Military Injuries to the Hand and Fingers. [R] . Cohen, J. 1977

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Association study of SNPs related finger bone development and digit ratio [J] . Dang Jie ,Zhang Jing ,Lu Hong . 解剖学杂志 . 2021,第S01期
• 3. 6RA70全数字调速装置应用于3#飞剪控制系统 [C] . 王杨 ,王永强 ,姜明 . 2011塑性成形过程中钢材组织性能预报与控制技术学术研讨会 . 2011
• 4. 锤击声学法锚杆轴力监测装置的设计与分析 [A] . 窦传浩 . 2016