首页> 外国专利> DNA CHIP IMAGE SPOT VALIDITY ASSESSING DEVICE, DNA CHIP IMAGE SPOT VALIDITY ASSESSING METHOD, AND DNA CHIP IMAGE SPOT VALIDITY ASSESSING PROGRAM

DNA CHIP IMAGE SPOT VALIDITY ASSESSING DEVICE, DNA CHIP IMAGE SPOT VALIDITY ASSESSING METHOD, AND DNA CHIP IMAGE SPOT VALIDITY ASSESSING PROGRAM

机译:DNA芯片图像点有效性评估装置,DNA芯片图像点有效性评估方法和DNA芯片图像点有效性评估程序

摘要

The invention makes it possible to prevent erroneous detection based on contamination or based on a pseudo-spot in a DNA chip image, and to improve the accuracy of examinations employing DNA chips. A device for assessing the validity of spots in a DNA chip image obtained by capturing an image of the DNA chip, to which probes have been fixed, in a state in which a labeled specimen has been bound to the probes, the device being provided with: a multi-stage binarization processing unit which creates a plurality of binarized images from the DNA chip image using, as thresholds to be used in an image binarization process, a plurality of thresholds distributed over the entire range of brightness in the DNA chip image; a spot shape and position detecting unit which detects the shapes and positions of spots in the binarized images; and a spot shape and position assessing unit which assesses the acceptability of the spot shapes and positions detected by the spot shape and position detecting unit.
机译:本发明使得可以防止基于污染或基于DNA芯片图像中的伪斑点的错误检测,并且可以提高使用DNA芯片的检查的准确性。提供一种用于在通过将已固定有探针的DNA芯片的图像捕获而获得的DNA芯片图像中的斑点的有效性进行评估的装置,其中已将标记的样本结合到探针上,该装置具有:多级二值化处理单元,使用在DNA芯片图像的整个亮度范围内分布的多个阈值作为图像二值化处理中使用的阈值,从DNA芯片图像生成多个二值化图像;点形状和位置检测单元,其检测二值化图像中的点的形状和位置;斑点形状和位置评估单元,评估由斑点形状和位置检测单元检测到的斑点形状和位置的可接受性。

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