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Use of a fluoropolymer as a contrast agent for imaging by magnetic resonance imaging (MRI) 19F solid state scaffold comprising said polymer and use thereof

机译:含氟聚合物作为造影剂用于通过包含所述聚合物的磁共振成像(MRI)19F固态支架进行成像的用途及其用途

摘要

Use of a fluorinated polymer having a glass transition temperature (Tg) below 40 ° C, preferably below 20 ° C, more preferably below 0 ° C, even more preferably below -40C as forming component imaging or contrast agent imaging magnetic resonance imaging (MRI) 19F of a solid object, the solid object that mark imaging or contrast agent, characterized in comprising that the solid object further comprises at least one non-fluorinated polymer wherein the fluoropolymer and at least one fluoropolymer not are joined together by covalent or non-covalent, wherein the at least one non-fluorinated polymer is noncovalently bound to the at least one fluoropolymer by hydrogen bond and wherein the at least one fluorinated polymer not bonded via hydrogen bonding is obtained from at least one monomer selected from the group consisting of urethane, urea, bisurea, ureidopyrimidone and combinations thereof.
机译:玻璃化转变温度(Tg)低于40°C,优选低于20°C,更优选低于0°C,甚至更优选低于-40°C的氟化聚合物作为形成成分成像或造影剂成像磁共振成像(MRI)的用途19 F)固体物体,该固体物体标记成像剂或造影剂,​​其特征在于,该固体物体还包含至少一种非氟化聚合物,其中该氟聚合物和至少一种未通过共价键或非氟键连接的氟聚合物结合在一起。共价键,其中所述至少一种非氟化聚合物通过氢键非共价键合至所述至少一种氟聚合物,并且其中所述至少一种未通过氢键键合的氟化聚合物由选自聚氨酯的至少一种单体获得,尿素,双脲,脲基嘧啶酮及其组合。

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