7-dodecanoxy-naringenin and 7,4'-didodecanoxy-naringenin and method for simultaneously obtaining 7-dodecanoxy-naringenin and 7,4'-didodecanoxy-naringenin

摘要

the object of the application is 7 - dodekanoksynaringenina and 7,4 '- didodekanoksynaringenina and process for the production of these compounds.the invention is that the substrate, which is naringenina model 1 is inserted, potassium carbonate k2co3 and 1 - jodododekan in mole ratio of at least 1:1.5: 5 and the minimum amount of organic solvent, which is a mixture of reaction.which protects against light and leaves from 105 to 120 degrees in temperature for a period of from 48 to 72 hours with constant stirring, after which the organic solvent vaporized,the following of a saturated solution of sodium chloride nacl and then lead extraction niemieszającym organic solvent with water.dried anhydrous magnesium sulphate and / or anhydrous sodium sulfate, the solvent vaporized, then the obtained extract is purified on column chromatography.