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Compounds with anti-tumor activity against cancer cells bearing EGFR or HER2 exon 20 mutations
Compounds with anti-tumor activity against cancer cells bearing EGFR or HER2 exon 20 mutations
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机译:对具有EGFR或HER2外显子20突变的癌细胞具有抗肿瘤活性的化合物
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摘要
The present disclosure provides methods of treating cancer in a patient determined to have an EGFR and/or HER2 exon 20 mutation, such as an insertion mutation, by administering a third-generation tyrosine kinase inhibitor, such as poziotinib or afatinib.
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