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ZNF746 - Antibodies to ZNF746 Phosphorylated Tyrosine Residue and the use

机译:ZNF746-ZNF746磷酸酪氨酸残基的抗体及其用途

摘要

The present invention relates to an antibody that detects tyrosine phosphorylation at a specific position of ZNF746, a Parkinson′s disease-derived protein, and enables early diagnosis of degenerative brain diseases including Parkinson′s disease, a kit and composition including the same, and a method for diagnosing degenerative brain diseases and screening for related drugs using the same. The antibody and the like of the present invention has the effect of early detection of degenerative brain diseases, especially Parkinson′s disease, to provide patients with appropriate therapeutic agents and methods of treatment.
机译:本发明涉及一种在帕金森氏病来源的蛋白质ZNF746的特定位置检测酪氨酸磷酸化的抗体,其能够早期诊断包括帕金森氏病在内的变性脑疾病,其试剂盒和组合物,以及一种诊断变性性脑疾病并使用其筛选相关药物的方法。本发明的抗体等具有及早发现退化性脑疾病,特别是帕金森氏病的作用,从而为患者提供合适的治疗剂和治疗方法。

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