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2.5 Biomarker for identification of genes related to inflammatory response after exposure to particulate matter 2.5 using human placenta cell line and the identification method using thereof

机译:2.5使用人胎盘细胞系鉴定与颗粒物接触后炎症反应相关基因的生物标记物2.5及其鉴定方法

摘要

The present invention is useful for determining the monitoring and the risk of fine dust (PM 2.5) of less than 2.5 micrometers, and is useful as a tool to identify the toxic action mechanism caused by PM 2.5, And a method for confirming the expression of messenger RNA (mRNA) in fine dusts of 2.5 micrometers or less using the kit. The kit for confirming exposure of micro-dusts of less than 2.5 micrometer according to the present invention and the method for confirming the expression of messenger RNA on micro-dusts of less than 2.5 micrometers using two kinds of micro- .5) It is useful for monitoring PM2.5 and determining the risk of PM2.5 by using inflammation related genes whose expression is changed by exposure as a biomarker. It is a tool to identify the toxic mechanism caused by PM2.5 It can be useful.
机译:本发明对于确定小于2.5微米的细粉尘(PM 2.5)的监测和风险是有用的,并且作为鉴定由PM 2.5引起的毒性作用机理的工具,以及用于确认PM2.5表达的方法是有用的。使用试剂盒,可在2.5微米或更小的细尘中使用信使RNA(mRNA)。根据本发明的用于确认小于2.5微米的微尘暴露的试剂盒,以及使用两种微孔来确认小于2.5微米的微尘上的信使RNA表达的方法。.5)有用的通过使用炎症相关基因(其表达因暴露而改变)作为生物标记物来监测PM2.5并确定PM2.5的风险。它是鉴定PM2.5引起的毒性机制的工具。

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