A mouthpiece (76) is detachably attached to the maxillary teeth dentition of a patient. A mouthpiece body (78) has an approximately uniform thickness. A mandibular teeth dentition impression (84) in an optimized chewing occlusal jaw position that balances the systemic basal muscle tone of the patient is formed on the occlusal surface of the mouthpiece body (78). When the patient attaches the mouthpiece (76) to the maxillary teeth dentition to achieve a chewing occlusal state or a resting occlusal state, the mandibular teeth dentition is induced to a proper positional relationship that balances a systemic basal muscle tone with respect to the maxillary teeth dentition due to the tongue/jaw position reflex and masseter/jaw position reflex of the patient, caused by attaching the mouthpiece (76), whereby a systemic pain symptom can be resolved or greatly relieved.
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