Avatar dendritic cells: the neoantigen natural killer T-cell chemo immuno radiation composition inducing immunogenic cell death

摘要

Contemplated compositions and methods counteract evasive measures of a tumor by rendering access to the tumor microenvironment, tagging the tumor microenvironment with chemoattractant and/or cytokines, delivering or facilitating a cell-based therapy in the tumor microenvironment while providing inhibition of immune suppressor cells in the tumor microenvironment.