DETECTION OF BIOMARKERS ASSOCIATED WITH BRUGADA SYNDROME

摘要

A method of detecting target autoantibodies to actin, connexin-43 and keratin in a mammal is provided. The comprises contacting a biological sample obtained from the mammal with each of actin, connexin-43 and keratin or with antigenic fragments thereof; and detecting the presence of the target autoantibodies in the sample by detecting binding of the target autoantibodies to each of the antigens. The method is useful to diagnose Brugada Syndrome.