--3-O--D-6-- Composition for preventing and treating nephrotoxicity comprising gamma-Pyrone-3-O--D-6-galloyl-glucopyranoside isolated from Euphorbia ebracteolata var. coreana Hurus

摘要

The present invention relates to a composition for preventing and treating diseases due to nephrotoxicity, comprising γ-pyrone-3-O-β-D-(6-galloyl)-glucopyranoside isolated from Euphorbia ebracteolata var. coreana Hurus., and when an existing anticancer drug, cisplatin, is administered, a pharmaceutical composition of the present invention, comprising γ-pyrone-3-O-β-D-(6-galloyl)-glucopyranoside as an effective component, can enhance the anticancer efficacy of cisplatin while suppressing cisplatin-induced renal cell death, and thus can prevent and treat diseases due to nephrotoxicity induced by anticancer drugs.