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METHOD FOR PREPARING AGENT FOR TREATING INFLAMMATORY DISEASES OF UPPER AND LOWER AIRWAYS

机译:治疗上,下气道炎性疾病的制剂的方法

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for preparing an agent for treating inflammatory diseases of the upper and lower airways. Method for preparing an agent for treating inflammatory diseases of upper and lower airways, by grinding plant material to nanopowder, wherein aspen bark (Populus tremula L) is ground to particle size of 1–2 mm, dried to moisture content of 8–10 %, nanodispersed in roller-type mill to particle size of 50–150 nm, then subjected to continuous extraction by repercolation, combined solution after settling is concentrated in vacuum to 70 % of dry substances at temperature of 50 °C with subsequent drying of the powder in vacuum to 3.8–5.5 wt. % content of salicin, arabinogalactanes 4.2–10.1 wt. %, polyphenols 3.9–7.2 wt. %.;EFFECT: method described above enables to obtain an agent with high output of a complex of biologically active substances, high efficiency of treating respiratory organs in upper and lower airway damages, fewer side effects, high availability of biologically active substances.;1 cl, 2 ex
机译:领域:医学;药物:本发明涉及制药工业,即一种用于制备治疗上呼吸道和下呼吸道炎性疾病的药剂的方法。通过将植物材料研磨成纳米粉来制备用于治疗上呼吸道和下呼吸道炎性疾病的药剂的方法,其中将白杨树皮(Populus tremula L)研磨成1-2 mm的颗粒大小,干燥至水分含量为8-10%纳米分散在辊式磨机中,粒度为50–150 nm,然后通过重凝进行连续萃取,沉降后的合并溶液在50°C的温度下真空浓缩至70%的干燥物质,随后干燥粉末在真空中至3.8–5.5 wt。水杨素,阿拉伯半乳糖烷的含量%4.2–10.1 wt。 %,多酚3.9-7.2 wt。效果:上述方法能够获得一种具有高产量的生物活性物质复合物,高效率地治疗上呼吸道和下呼吸道损伤的呼吸器官,副作用少,生物活性物质利用率高的药剂。 cl,前2个

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