高濃度の抗ＶＥＧＦ抗体を含有する安定状態のタンパク質溶液製剤

摘要

Problem to be solved.Solution: an anti VEGF antibody which is formulated as a high concentration aqueous pharmaceutical composition suitable for injection, preferably intravitreal injection.The aqueous pharmaceutical composition is useful for delivering high concentration of antibody active components to patients without high levels of antibody agglutination and without high levels of non visible granules.The aqueous composition of the present invention comprises antibodies having at least 50 mg \/ ml of concentration.The aqueous pharmaceutical composition of the present invention comprises a sugar, a buffer, and a surfactant.No selection