Studies of Substituent and Solvent Effects on Solvolysis Reactions. 1: The Effect of Polar alpha-Substituents on the Rate of Alkaline Ester Hydrolysis in Water at Different Temperatures

摘要

The rate constants and the activation parameters for the saponification of mono, di and tri halogeno-hydroxy, methoxy and ethoxy-methyl acetates and ethytl acetates were determined from the rapid changes in the conductivity during the course of the reaction. The effect of the substituent is explained by the electrostatic interaction of the reaction partners.