A Study of the Qualitative and Quantitative Correlation of the Results of the Hi Test, the Neutralization Test in Tissue Culture, and the Agar Gel Diffusion Test in the Study of Human Sera from West Nile Fever Foci in Azerbaydzhan.

摘要

The results of serological and virological reconnaissance of recent years has made it possible to establish a rather wide distribution of the West Nile fever virus on the territory of the Soviet Union. In an investigation of human and animal sera, collected in the fall and winter of 1969 in six regions of Azerbaydzhan, by means of a HI test with the antigens of ten group A and group B arboviruses, the presence of West Nile fever foci was established in regions located in the central portion of the Kura river. In investigating human sera from these regions, besides the previously used HI tests and the neutralization test, the agar gel diffusion (AGD) test, which is coming into constantly more extensive use in the diagnosis of arbovirus infections was also used. A study was made of the qualitative and quantitative degree of correlation between the results of the HI tests, the neutralization test and the AGD test, and we studied the possibility of using the AGD test for studying the immunological state of the population in the West Nile fever foci. (Author)