How many factor antisera can be found for serogroup 6 Streptococcus pneumoniae?

摘要

We read the article of Jacobs et al. (3) with interest. The authors reported they could identify serotype 6C Streptococcus pneumoniae using factor 6d, which was developed by Statens Serum Institut, Copenhagen, Denmark.We immunized a rabbit with one serotype 6C isolate identified with a monoclonal antibody (MAb6C) in the U.S. lab in which the new type was found. Based on absorption with se-rotypes 6A and 6B and the Quellung test (6), we got the specific antiserum for MAb6C after absorption with 6A and 6B. The antiserum identified 10 serotype MAb6C isolates among 91 traditional serotype 6A isolates, just like the multibead assay.