Left ventricular mass regression after aortic valve replacement with the TTK Chitra (TM) monoleaflet tilting disc valve

摘要

ObjectiveTo study the extent of left ventricular (LV) mass regression in aortic stenosis after aortic valve replacement with the TTK Chitra (TM) tilting disc valve.Methods and materialsThis study included patients with severe isolated aortic stenosis (AS), admitted in our department. They had aortic valve replacement (AVR) with the TTK Chitra (TM) tilting disc valve, between January 2008 and December 2010. Data were collected from consecutive forty-eight patients. LV mass and diametric and functional parameters were recorded preoperatively and compared with echocardiography after 3 months, 6 months, then yearly, up to 3 years.Results70.8 of the patients were males and 29.2 were females. The mean duration of illness was 37.92 +/- 25.87 months. The mean LV ejection fraction increased 3 months after surgery (61.56 +/- 10.10 to 69.31 +/- 9.34) with a sustained increase for the next 3 years. The mean LV end-diastolic diameter decreased (50.16 +/- 6.05 mm to 45.69 +/- 5.93 mm) after 3 months of surgery, with a sustained decrease for the next 3 years. The mean LV end-systolic diameter decreased (32.84 +/- 6.96 mm to 29.41 +/- 5.86 mm) after 3 months of surgery and then showed a sustained decrease for the next 3 years. The LV mass assessed with echocardiography regressed from 324.65 +/- 97.77 g before surgery to 252.64 +/- 71.12 g after 3 months and then showed a sustained decrease over the next 3 years.ConclusionSignificant LV mass regression occurred after AVR with the TTK Chitra (TM) valve. The maximum reversal was found to be within the first 3 months after surgery with sustained beneficial improvement for the next 3 years.