Photolithographic Boronate Affinity Molecular Imprinting: A General and Facile Approach for Glycoprotein Imprinting

摘要

Molecularly imprinted polymers (MIPs), as economical and stable mimics of antibodies and enzymes, have found important applications, such as chemical separation and catalysis. The imprinting of proteins is challenging, which is due to conformational changes during polymerization and slow mass transfer in the polymers. Although several strategies, such as surface imprinting, epitope imprinting, and Pickering emulsions, have been proposed to solve these issues, the imprinting of proteins still remains a challenge.