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Answer to march 2011 photo quiz.

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Both the arterial embolus and the aortic valve tissue grew Histoplasma capsulatum. Histoplasma urine antigen tests performed on a specimen collected the same week as the valve replacement were negative, as were results for complement fixation antibodies. Postoperatively, the patient received approximately 2 weeks of treatment with intravenous lipid complex amphotericin B, followed by 9 months of treatment with oral itraconazole solution (200 mg twice a day for 4 months and 5 additional months of 200 mg once daily). Seven years later, the patient was physically active and without evidence of valvular dysfunction.

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