Atom- and Step-Economical Pathway to Chlral Benzobicyclo-2.2.2octenones through Carbon-Carbon Bond Cleavage

摘要

It has become an imperative issue to improve the step as well as atom economy of organic synthesis. A highly atom-economical method to construct carbon frameworks could arise if an unsaturated organic functionality is directly inserted into a carbon-carbon single bond. Such an insertion reaction also dispenses with functional group manipulations to significantly reduce the steps required for construction of a particular organic skeleton.