Asymmetric halogen-promoted cychzations have been the object of extensive investigations, the ultimate aim being the emulation of nature's remarkable ability to construct architecturally complex enantiopure halogenated compounds from prochiral precursors. Progress has been slow, but significant advances have recently been made in iodo-, bromo-, and chlorocyclizations. A catalytic enantioselective fluorocycli-zation induced by an electrophilic fluorinating reagent has not been reported to date.
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