Modular combinations of organocatalytic reactions into cascades has attracted increasing attention in organic synthesis, as it enables the efficient and stereoselective construction of complex molecules from simple precursors, and greatly circumvents time, energy, and yield losses associated with traditional multistep syntheses.Although the underlying mechanistic principles of individual steps seem to be well understood and even used in the design of new cascades, the mechanistic details of these complex reactions are largely unexplored.
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