In the last decade organocatalysis has developed into an essential third branch of asymmetric catalysis that now complements the fields of metal and enzyme catalysis and provides widely applicable methods for efficient organic synthesis. Especially the combination and integration in cooperative catalysis such as domino reactions and the recent efforts in combining organocatalysis with metal activation demonstrate that the potential of organocatalysis for the development of new activation modes in selective organic synthesis is still not fully uncovered.
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