Anion Relay Chemistry: Access to the Type II ARC Reaction Manifold through a Fundamentally Different Reaction Pathway Exploiting 1-Oxa-2-silacyclopentanes and Related Congeners

摘要

Type I and II anion relay chemistry (ARC) exploiting 1,m-Brook rearrangements (Scheme 1A and B, respectively), comprise an effective set of synthetic tactics that unite multiple components, in a single reaction flask, that permits rapid access to architecturally diverse polyketide and alkaloid molecular arrays.