Copper-Catalyzed Regio- and Eitantioselective Hydroamination of Alkenes with Hydroxylamines

摘要

The development of new methods for the asymmetric synthesis of amines from readily available monomer feedstocks is an important research area that has profound implications for expedited drug discovery and the production of pharmaceuticals. In this context, the catalytic hydroamination of alkenes with amines is a powerful transformation that holds promise to rapidly deliver value-added chiral amines from simple and accessible starting materials.