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首页> 外文期刊>Angewandte Chemie >Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide
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Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

机译:基于轮烷的前肽:生物活性五肽的保护和酶促释放

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摘要

Rotaxane and pseudorotaxane architectures are starting to attract interest as a means of molecularly encapsulating substrates for potential biological applications.Nano-valves' that can store and release cargo molecules have been developed, and the encapsulation of squaraine dyes within rotaxanes has been shown to enhance dye fluorescence and stability as well as imparting different cell-localization propensities on the substrates.
机译:轮烷和假轮烷结构作为分子封装底物的一种手段,开始引起人们的兴趣,用于潜在的生物应用。已经开发出可以储存和释放货物分子的纳米阀门,并且将方形染料封装在轮烷中已被证明可以增强染料的荧光和稳定性,并在底物上赋予不同的细胞定位倾向。

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