On‐Line Assessment of Metabolic Activities Based on Culture Redox Potential and Dissolved Oxygen Profiles During Aerobic Fermentation

摘要

AbstractWe report here on the utility of on‐line culture redox potential and dissolved oxygen measurements to identify metabolic changes in fermentation byCorynebacterium glutamicumunder aerobic conditions. Metabolic changes were identified by observing discrepancies in the profile of culture redox potential and dissolved oxygen. On the basis of these measurements, we can identify the end of the lag phase, threonine exhaustion, and glucose exhaustion during fermentatio