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机译:Asymmetric Cation-Olefin Monocyclization by Engineered Squalene-Hopene Cyclases
Givaudan Schweiz AG, Ingredients Res, Fragrances S&T, Kemptpk 50, CH-8310 Kemptthal, Switzerland;
Givaudan Int SA, Sci & Technol, Kemptpk 50, CH-8310 Kemptthal, Switzerland;
Greifswald Univ, Inst Biochem, Dept Biotechnol & Enzyme Catalysis, Felix Hausdorff Str 4, D-17487 Greifswald, GermanyZurich Univ Appl Sci, Life Sci & Facil Management, Einsiedlerstr 31, CH-8820 Wadenswil, Switzerland;
chemoenzymatic synthesis; cyclization; protein engineering; squalene-hopene cyclases; substrate engineering;