Vaccine Development against Cryptocaryoniasis: A Review

摘要

Cryptocaryon irritans is an obligate parasitic ciliate of marine teleosts and is the causative agent of cryptocaryoniasis (marine white spot disease). The parasite infects the skin and gills of marine teleosts and often causes mass mortality in heavily infected fish. Therefore, this parasite is a major threat to marine aquaculture in tropical and subtropical waters, and effective control methods are required. Interestingly, it was reported that fish infected with the parasite acquired protective immunity against it, and it was suggested that a vaccine strategy could be realized. Since then, many researchers have attempted to develop vaccines against cryptocaryoniasis. This review presents the current research on vaccine development against cryptocaryoniasis to provide references for future experimental studies and propose future research directions.