The hypercoagulability of intravenous immunoglobulin.

摘要

H&O What is intravenous immunoglobulin? MM Intravenous immunoglobulin (IVIG) is a solution of human plasma-derived immunoglobulin containing an extensive range of immune antibodies that may protect against human pathogens or antigens. It has been in use for more than 2 decades, for conditions such as idiopathic thrombocytopenic purpura, chronic lymphocytic leukemia, and HIV infection. The number of diseases that are being treated with IVIG continues to increase (Table 1). Shortly after the introduction of IVIG agents, they were found to be effective in the treatment of autoimmune and inflammatory disorders. IVIG can sometimes achieve a cure in patients who do not respond to first-line therapies.