The Importance of Accuracy in HER2 Testing.

摘要

AG Assessment of human epidermal growth factor receptor 2 (HER2) status can identify patients who would benefit from anti-HER2 therapy, either in the early breast cancer setting or in the metastatic breast cancer setting. Anti-HER2 therapy has been shown to improve disease-free survival and overall survival in patients with early breast cancer, and to increase progression-free survival and overall survival in patients with advanced breast cancer. HER2 is an important biomarker because it has consequences. If we fail to detect HER2, we fail to give patients the appropriate therapy, and they may die from incurable disease.