Computerized Cognitive Training in Pediatric Sickle Cell Disease: A Randomized Controlled Pilot Study

摘要

Objective: The current study assessed the feasibility of a computerized cognitive intervention, Cogmed, in a sample of youth with SCD (ages 8-16 years). If deemed feasible, the secondary aim of the study was to evaluate preliminary efficacy. Methods: Youth with SCD were randomized to a waitlist control or the Cogmed program. Data pertaining to cognitive functioning, psychosocial functioning, and disease characteristics were obtained from participants pre- and postintervention. In addition, data regarding participant interest, consent rate, and intervention compliance were tracked. Results: Eighteen participants (M = 12.2 years old) enrolled in this study. Results indicate that the majority of prospective families approached about the intervention (82%) expressed interest in participating in the study, although less than 25% of interested participants enrolled. Three of 18 consenting participants completed the intervention. Cognitive, medical, and psychosocial factors related to feasibility and compliance were identified. Conclusions: Taken together, the results of this study suggest that there is a high degree of interest for this type of intervention but poor feasibility in practice. Implications and future directions are discussed.