Characterization of defined sulfated heparin-like oligosaccharides by electrospray ionization ion trap mass spectrometry

摘要

Glycosaminoglycans (GAG) as long, unbranched polysaccharides are major components of the extracellular matrix. Many studies provided additional evidence of a specific binding between mediators and sulfated GAG, at which the sulfation code-which means the number and positions of sulfate groups along the polysaccharide chain-plays an important role.