Effect of Botulinum toxin-A treatment on ankle and knee kinematics in spastic CP patients based on combination of treated muscles

摘要

Spasticity is a common problem that interferes with gait in cerebral palsy (CP). Botulinum toxin-A (BoNT-A) injection is widely used in the management of spasticity. Conclusions about the effect of BoNT-A treatment are complicated by the heterogeneity in impairments and level of severity in CP. Analysing subgroups of spastic CP (SCP) patients could be helpful to distinguish which patients will benefit most of BoNT-A treatment. In this study we evaluated SCP children walking with increased knee flexion and incomplete foot contact in Midstance (MSt). We investigated whether the gait pattern normalized in subgroups that received medial hamstrings (HM) and/or gastrocnemius (GM) injections, with the aim to improve knee extension and ankle dorsiflexion.