Imprinted Photonic Polymers for Chiral Recognition

摘要

Molecular imprinting is a well-established and facile technique to synthesize molecularly imprinted polymers (MIPs)with specific molecular-recognition sites for a large variety of applications, such as chromatographic separations, membranes, catalysis, biosensors, and artificial antibodies.[1–12] Molecular recognition and separation is generally based on bulk polymers, which have the disadvantages of long diffusion paths and the absence of accessible cavities for the analyte in the bulk, thus resulting in low specific capacities and long response times. Recently, the groups of Mosbach and Sellergren overcame these drawbacks of bulk MIPs by using hierarchical imprinting of template molecules on the surface of a porous silica support.