Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study

Tack Laura; Lefebvre Tessa; Lycke Michelle; Pottel Lies; Cool Lieselot; Ketelaars Lore; De Zutter Jolien; Martens Evi; Pottel Hans; Stellamans Karin; Van Eygen Koen; Werbrouck Patrick; Vergauwe Philippe; Wildiers Hans; Schofield Patricia; Boterberg Tom; Debruyne Philip R.

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Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study

机译：脆弱的癌症患者在II期和III期肿瘤学登记试验中的脆弱性陈述：案例对照研究

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Objectives: We aimed to determine the proportion of "fit" versus "vulnerable" older patients with cancer included in phase II and Ill oncology registration trials, as compared to the proportions in a real life oncology setting.

机译：目标：我们旨在确定与实际局部肿瘤学环境中的比例相比，确定癌症中包含的癌症的“脆弱”的老年患者的比例。

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来源
《Journal of geriatric oncology》 |2020年第2期|共7页
作者
Tack Laura; Lefebvre Tessa; Lycke Michelle; Pottel Lies; Cool Lieselot; Ketelaars Lore; De Zutter Jolien; Martens Evi; Pottel Hans; Stellamans Karin; Van Eygen Koen; Werbrouck Patrick; Vergauwe Philippe; Wildiers Hans; Schofield Patricia; Boterberg Tom; Debruyne Philip R.;
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作者单位

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Dept Psychol Kortrijk Belgium;

Gen Hosp Groeninge Dept Psychol Kortrijk Belgium;

Gen Hosp Groeninge Dept Psychol Kortrijk Belgium;

Catholic Univ Leuven Kulak Dept Publ Hlth &

Primary Care Kulak Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

Gen Hosp Groeninge Dept Urol Kortrijk Belgium;

Gen Hosp Groeninge Dept Gastroenterol Kortrijk Belgium;

Univ Hosp Leuven Dept Med Oncol Leuven Belgium;

Sheffield Hallam Univ Sheffield S Yorkshire England;

Univ Ghent Dept Radiat Oncol &

Expt Canc Res Ghent Belgium;

Gen Hosp Groeninge Canc Ctr Dept Med Oncol Kortrijk Belgium;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
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1. Re: Underrepresentation of Vulnerable Older Patients with Cancer in Phase II and III Oncology Registration Trials: A Case-Control Study [J] . Griebling Tomas L. The Journal of Urology . 2020,第5期

机译：Re：II期和III期癌症患者的脆弱性老年患者的代表性，案例对照研究
2. Southwest oncology group S0008: A Phase III trial of high-dose interferon alfa-2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin-2 and interferon in patients with high-risk melanoma-an intergroup study of cancer and leukemia group B, children's oncology group, eastern cooperative oncology group, and southwest oncology group [J] . FlahertyL.E., OthusM., AtkinsM.B., Journal of Clinical Oncology . 2014,第33期

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3. Phase II trial of postoperative adjuvant cisplatin and etoposide in patients with completely resected stage I-IIIa small cell lung cancer: The Japan Clinical Oncology Lung Cancer Study Group Trial (JCOG9101) [J] . Ryosuke Tsuchiya, Kenji Suzuki, Yukito Ichinose, The journal of thoracic and cardiovascular surgery . 2005,第5期

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机译：完全切除I-IIIa期小细胞肺癌患者术后辅助用顺铂和依托泊苷的II期临床试验：日本临床肿瘤学肺癌研究组试验（JCOG9101）

Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study

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