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Colon cancer.

机译:结肠癌。

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摘要

Colon cancer is one of the leading tumours in the world and it is considered among the big killers, together with lung, prostate and breast cancer. In the recent years very important advances occurred in the field of treatment of this frequent disease: adjuvant chemotherapy was demonstrated to be effective, chiefly in stage III patients, and surgery was optimized in order to achieve the best results with a low morbidity. Several new target-oriented drugs are under evaluation and some of them (cetuximab and bevacizumab) have already exhibited a good activity/efficacy, mainly in combination with chemotherapy. The development of updated recommendations for the best management of these patients is crucial in order to obtain the best results, not only in clinical research but also in every-day practice. This report summarizes the most important achievements in this field and provides the readers useful suggestions for their professional practice.
机译:结肠癌是世界上主要的肿瘤之一,与肺癌,前列腺癌和乳腺癌一起被认为是最大的杀手。近年来,在这种常见疾病的治疗领域中取得了非常重要的进展:辅助化疗被证明是有效的,主要在III期患者中,并且对手术进行了优化,以便在低发病率的情况下获得最佳效果。几种新的靶向药物正在接受评估,其中一些药物(西妥昔单抗和贝伐单抗)已经表现出良好的活性/功效,主要是与化学疗法联合使用。为了获得最好的结果,不仅在临床研究中而且在日常实践中,为这些患者的最佳管理制定更新的建议至关重要。本报告总结了该领域最重要的成就,并为读者的专业实践提供了有益的建议。

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