Palladium-Catalyzed Coupling Reactions

摘要

The great importance of palladium-catalyzed cross-coupling reactions and C—C bond formation in modern organic chemistry was confirmed by the award of the 2010 Nobel Prize in Chemistry to Heck, Negishi, and Suzuki. The usefulness of related chemical named reactions, i.e., the Sonogashira, Stille, Kumada, and Hiyama couplings, should not be forgotten, as they form a useful synthetic toolbox in industrial processes (e.g., for pharmaceuticals, agrochemicals, molecular materials) and academic endeavors (in total synthesis, multicomponent reactions, fundamentals of catalysis, etc.).