Nickel-Catalyzed α-Arylation of Ketones with Phenol Derivatives

摘要

The nickel-catalyzed a-arylation of ketones with readily available phenol derivatives (esters and carbamates) provides access to useful a-arylketones. For this transformation, 3,4-bis(dicyclohexylphosphino)thiophene (dcypt) was identified as a new, enabling, air-stable ligand for this transformation. The intermediate of an assumed C—O oxidative addition was isolated and characterized by X-ray crystal-structure analysis.