A Cobalt-Catalyzed Alkene Hydroboration with Pinacolborane

摘要

An extremely efficient cobalt catalyst for the hydroboration of both vinylarenes and aliphatic a-olefins with pinacolborane is described, providing the anti-Markovnikov products with excellent regio- and chemoselectivity, broad functional-group tolerance, and high turnover numbers (up to 19800). The alkene hydroboration route is further extended to a two-step, one-pot hydroboration and cross-coupling of alkylboronates with aryl chlorides.