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Bioinorganic Medicinal Chemistry

机译:生物无机药物化学

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摘要

A little over 40 years after the discovery of cis-diammindi- chloroplatin(II) (cisplatin) by Barnett Rosenberg, diagnostic and therapeutic applications of metal complexes have significantly expanded beyond the use of platinum complexes in anticancer chemotherapy. During the last 10 to 15 years, the field of bioinorganic medicinal chemistry has seen a tremendous development both in terms of classes of compounds studied as well as breadth of applications in human medicine. Thus, it is certainly time now to summarize these interesting developments in one coherent book. Enzo Alessio from the University of Trieste, himself actively involved in the development of antimetastatic ruthenium complexes, has brought together leading experts in the field from around the world to cover all relevant aspects of medical applications of inorganic compounds in the thirteen chapters of Bioinorganic Medicinal Chemistry.
机译:巴内特·罗森伯格(Barnett Rosenberg)发现顺二氨二氯氯铂(II)(顺铂)大约40年后,金属配合物的诊断和治疗应用已大大扩展,超出了铂配合物在抗癌化学疗法中的用途。在过去的10到15年中,无论是研究的化合物种类还是在人类医学中的广泛应用,生物无机药物化学领域都取得了长足的发展。因此,现在肯定是在一本连贯的书中总结这些有趣的发展的时候了。的里雅斯特大学的恩佐·阿莱西奥(Enzo Alessio)积极参与了抗转移钌络合物的开发工作,汇集了来自该领域的领先专家,涵盖了生物无机药物化学的十三章中无机化合物医学应用的所有相关方面。 。

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